NR 451/439 Your capstone change project begins this week when you identify a problem that you judge needs to experience a change in order to produce better patient outcomes. Formulate a significant clinical question that will be the basis for your capstone change project. Relate how you developed the question. Describe the importance of this question to your clinical practice. Define meta-analysis, and explain how this relates to evidence -based practice (EBP). Describe what a research-practice gap is.